Are digital c.elegans coming soon? Their entire genome has been mapped and a virtual connectome has been published, now can we simulate the entire biology of the worm or worms with different mutations? Alexis Madrigral discusses this topic in a provoking article in The Atlantic:
…What’s so hard about simulating its behavior?
We don’t know how to simulate every single protein and nucleic acid in a cell. And even if we could, it would be computationally staggering to try to model each and every cell in the worm down to that atomic level, figuring out each and every molecular interaction inside these densely packed cells. No experiments can output that data.